Llandrillo may refer to one of the following in Wales:
- Llandrillo, Denbighshire, a village near Corwen
- Coleg Llandrillo Cymru, a multi-campus college in Conwy and Denbighshire
- Grŵp Llandrillo Menai, the umbrella group of north-Wales colleges
- Rhos-on-Sea (or Llandrillo-yn-Rhos), a suburb of Colwyn Bay in Conwy