Luteusin A is an azaphilone monoamine oxidase inhibitor produced by Talaromyces luteus.[2]

Luteusin A
Names
Preferred IUPAC name
(7S,8R)-5-Chloro-3-[(1E,3E,5S)-3,5-dimethylhepta-1,3-dien-1-yl]-7,8-dihydroxy-7-methyl-7,8-dihydro-6H-2-benzopyran-6-one
Identifiers
3D model (JSmol)
ChemSpider
  • InChI=1S/C19H23ClO4/c1-5-11(2)8-12(3)6-7-13-9-14-15(10-24-13)17(21)19(4,23)18(22)16(14)20/h6-11,17,21,23H,5H2,1-4H3/b7-6+,12-8+/t11-,17+,19-/m0/s1
    Key: ZFOBGKZKFOAYTR-CZYMVTAPSA-N
  • InChI=1/C19H23ClO4/c1-5-11(2)8-12(3)6-7-13-9-14-15(10-24-13)17(21)19(4,23)18(22)16(14)20/h6-11,17,21,23H,5H2,1-4H3/b7-6+,12-8+/t11-,17+,19-/m0/s1
    Key: ZFOBGKZKFOAYTR-CZYMVTAPBB
  • CC[C@H](C)/C=C(\C)/C=C/C1=CC2=C(C(=O)[C@@]([C@@H](C2=CO1)O)(C)O)Cl
Properties
C19H23ClO4
Molar mass 350.84 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

References

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  1. ^ "KNApSAcK Metabolite Information - C00053446". www.knapsackfamily.com.
  2. ^ Yoshida, E; Fujimoto, H; Yamazaki, M (1996). "Isolation of three new azaphilones, luteusins C, D, and E, from an ascomycete, talaromyces luteus". Chemical & Pharmaceutical Bulletin. 44 (2): 284–7. doi:10.1248/cpb.44.284. PMID 8998836.