Mab-21-like 2 (C. elegans) is a protein that in humans is encoded by the MAB21L2 gene.[5]
| MAB21L2 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| Aliases | MAB21L2, MCOPS14, Mab-21-like 2 (C. elegans), mab-21 like 2, MCSKS14 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 604357; MGI: 1346022; HomoloGene: 7824; GeneCards: MAB21L2; OMA:MAB21L2 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Function
editThis gene is similar to the C. elegans MAB-21 cell fate-determining gene, a downstream target of transforming growth factor-beta signaling. It is thought that this gene may be involved in neural development. The protein encoded by this gene is primarily nuclear, although some cytoplasmic localization has been observed. [provided by RefSeq, Jul 2008].
References
edit- ^ a b c GRCh38: Ensembl release 89: ENSG00000181541 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000057777 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: Mab-21-like 2 (C. elegans)".
Further reading
edit- Mariani M, Baldessari D, Francisconi S, Viggiano L, Rocchi M, Zappavigna V, Malgaretti N, Consalez GG (December 1999). "Two murine and human homologs of mab-21, a cell fate determination gene involved in Caenorhabditis elegans neural development". Human Molecular Genetics. 8 (13): 2397–406. doi:10.1093/hmg/8.13.2397. PMID 10556287.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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