MBF may refer to:
- MBF, an Australian health insurance provider now merged with Bupa
- Marine's Best Friend, a Doom source port based on Boom
- One thousand board feet, a measurement in common use in the North American lumber industry
- Microsoft Binary Format, a floating point number format
- MBF Bioscience, a bioscience research software development company
- Minimum breaking force, a measurement for ropestrengths in kilonewtons (kN)
- Master of Banking and Finance
- Militärbefehlshaber in Frankreich (English: German Military Command in France), which administered Occupied France during World War II