MIS18BP1

MIS18 binding protein 1 is a protein that in humans is encoded by the MIS18BP1 gene. The gene is also known as LKNL2, M18BP1, C14orf106, and HSA242977.

MIS18BP1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1WGX
Identifiers
Aliases	MIS18BP1, C14orf106, HSA242977, KNL2, M18BP1, MIS18 binding protein 1
External IDs	OMIM: 618139; MGI: 2145099; HomoloGene: 10147; GeneCards: MIS18BP1; OMA:MIS18BP1 - orthologs
Gene location (Human) Chr. Chromosome 14 (human) Band 14q21.2 Start 45,203,190 bp End 45,253,540 bp
Gene location (Mouse) Chr. Chromosome 12 (mouse) Band 12|12 C1 Start 65,179,508 bp End 65,219,378 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in monocyte ventricular zone testicle epithelium of colon tendon of biceps brachii gonad ganglionic eminence buccal mucosa cell Achilles tendon rectum Top expressed in genital tubercle tail of embryo abdominal wall zygote medial ganglionic eminence primitive streak maxillary prominence renal corpuscle oocyte mandibular prominence More reference expression data BioGPS More reference expression data
Gene ontology Molecular function DNA binding protein binding DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component chromosome chromosome, centromeric region nucleus nucleoplasm Biological process cell division cell cycle CENP-A containing chromatin assembly regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55320 217653 Ensembl ENSG00000129534 ENSMUSG00000047534 UniProt Q6P0N0 Q80WQ8 RefSeq (mRNA) NM_018353 NM_172578 RefSeq (protein) NP_060823 NP_766166 Location (UCSC) Chr 14: 45.2 – 45.25 Mb Chr 12: 65.18 – 65.22 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Further reading

• Fujita Y, Hayashi T, Kiyomitsu T, Toyoda Y, Kokubu A, Obuse C, Yanagida M (January 2007). "Priming of centromere for CENP-A recruitment by human hMis18alpha, hMis18beta, and M18BP1". Dev. Cell. 12 (1): 17–30. doi:10.1016/j.devcel.2006.11.002. PMID 17199038.
• Maddox PS, Hyndman F, Monen J, Oegema K, Desai A (March 2007). "Functional genomics identifies a Myb domain-containing protein family required for assembly of CENP-A chromatin". J. Cell Biol. 176 (6): 757–63. doi:10.1083/jcb.200701065. PMC 2064049. PMID 17339379.
• Nousiainen M, Silljé HH, Sauer G, Nigg EA, Körner R (April 2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. Bibcode:2006PNAS..103.5391N. doi:10.1073/pnas.0507066103. PMC 1459365. PMID 16565220.