MXD, MxD, or mxd can refer to:

  • Manufacturing times Digital, a digital manufacturing institute based in Chicago, Illinois, U.S., that is part of Manufacturing USA
  • Modang language, a language spoken in East Kalimantan province, Indonesia, by ISO 639 code
  • Batik Air Malaysia, a regional airline from Malaysia, by ICAO code
  • Maximum latewood density, a facet of tree rings studied by dendroclimatology
  • .mxd, a file format for map data supported by ArcMap
  • Minoxidil, a medicine used to treat high blood pressure and hair loss, by Protein Data Bank ligand code
  • Marion Downs Airport, an airport in Marion Downs Station, Queensland, Australia; see List of airports by IATA airport code: M

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