MY-5445

MY-5445
Names
	Preferred IUPAC name N-(3-Chlorophenyl)-4-phenylphthalazin-1-amine
Identifiers
CAS Number	78351-75-4 ;
3D model (JSmol)	Interactive image;
ChemSpider	1308;
ECHA InfoCard	100.163.900
EC Number	636-069-4;
PubChem CID	1348;
UNII	F8CSS73B6A;
CompTox Dashboard (EPA)	DTXSID70229009 ;
	InChI InChI=1S/C20H14ClN3/c21-15-9-6-10-16(13-15)22-20-18-12-5-4-11-17(18)19(23-24-20)14-7-2-1-3-8-14/h1-13H,(H,22,24) Key: CEHQLKSLMFIHBF-UHFFFAOYSA-N; InChI=1/C20H14ClN3/c21-15-9-6-10-16(13-15)22-20-18-12-5-4-11-17(18)19(23-24-20)14-7-2-1-3-8-14/h1-13H,(H,22,24) Key: CEHQLKSLMFIHBF-UHFFFAOYAQ;
	SMILES C1=CC=C(C=C1)C2=NN=C(C3=CC=CC=C32)NC4=CC(=CC=C4)Cl;
Properties
Chemical formula	C20H14ClN3
Molar mass	331.80 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

MY-5445 is a relatively specific phosphodiesterase 5 inhibitor.^[1]^[2]

References

^ Nagendran, J; Archer, SL; Soliman, D; Gurtu, V; Moudgil, R; Haromy, A; St. Aubin, C; Webster, L; Rebeyka, IM; Ross, DB; Light, PE; Dyck, JR; Michelakis, ED (17 July 2007). "Phosphodiesterase Type 5 is Highly Expressed in the Hypertrophied Human Right Ventricle, and Acute Inhibition of Phosphodiesterase Type 5 Improves Contractility" (PDF). Circulation. 116 (3): 238–48. doi:10.1161/circulationaha.106.655266. PMID 17606845. S2CID 7612061.
^ Hagiwara, M; Endo, T; Kanayama, T; Hidaka, H (February 1984). "Effect of 1-(3-Chloroanilino)-4-phenylphthalazine (MY-5445), a Specific Inhibitor of Cyclic GMP Phosphodiesterase, on Human Platelet Aggregation". The Journal of Pharmacology and Experimental Therapeutics. 228 (2): 467–71. PMID 6141286.

This article about an organic compound is a stub. You can help Wikipedia by expanding it.