Mahane Yehuda may refer to:
- Mahane Yehuda (neighborhood), a historic neighborhood in Jerusalem, Israel
- Mahane Yehuda Market, an open-air marketplace in Jerusalem, Israel
- Mahane Yehuda, a part of south Petah Tikva
- "Mahane Yehuda", mounted guards company founded by Michael Halperin in 1891 (see Ness Ziona)