Major facilitator superfamily domain containing 2b

Major facilitator superfamily domain containing 2B is a protein that in humans is encoded by the MFSD2B gene.

MFSD2B
Identifiers
Aliases	MFSD2B, major facilitator superfamily domain containing 2B, SLC59A2
External IDs	OMIM: 617845; MGI: 3583946; HomoloGene: 47753; GeneCards: MFSD2B; OMA:MFSD2B - orthologs
Gene location (Human) Chr. Chromosome 2 (human) Band 2p23.3 Start 24,010,081 bp End 24,063,321 bp
Gene location (Mouse) Chr. Chromosome 12 (mouse) Band 12|12 A1.1 Start 4,912,440 bp End 4,924,359 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in blood monocyte bone marrow testicle bone marrow cells thymus gonad stromal cell of endometrium placenta granulocyte Top expressed in blood spleen yolk sac bone marrow neural layer of retina embryo human fetus granulocyte body of femur blastocyst More reference expression data BioGPS n/a
Gene ontology Molecular function sphingolipid transporter activity symporter activity transporter activity Cellular component membrane integral component of membrane plasma membrane integral component of plasma membrane Biological process lipid transport carbohydrate transport transmembrane transport organic substance transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 388931 432628 Ensembl ENSG00000205639 ENSMUSG00000037336 UniProt A6NFX1 Q3T9M1 RefSeq (mRNA) NM_001080473 NM_001346880 NM_001033488 RefSeq (protein) NP_001333809 NP_001028660 Location (UCSC) Chr 2: 24.01 – 24.06 Mb Chr 12: 4.91 – 4.92 Mb PubMed search
Wikidata
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Further reading

• Angers M, Uldry M, Kong D, Gimble JM, Jetten AM (December 2008). "Mfsd2a encodes a novel major facilitator superfamily domain-containing protein highly induced in brown adipose tissue during fasting and adaptive thermogenesis". Biochem. J. 416 (3): 347–55. doi:10.1042/BJ20080165. PMC 2587516. PMID 18694395.
• Bao L, Zhang Y, Wang J, Wang H, Dong N, Su X, Xu M, Wang X (October 2016). "Variations of chromosome 2 gene expressions among patients with lung cancer or non-cancer". Cell Biol. Toxicol. 32 (5): 419–35. doi:10.1007/s10565-016-9343-z. PMID 27301951. S2CID 17611299.