Malonate decarboxylase holo-(acyl-carrier protein) synthase

Malonate decarboxylase holo-(acyl-carrier protein) synthase (EC 2.7.7.66, holo ACP synthase, '2'-(5''-triphosphoribosyl)-3'-dephospho-CoA:apo ACP 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA transferase, MdcG, 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA:apo-malonate-decarboxylase adenylyltransferase, holo-malonate-decarboxylase synthase) is an enzyme with systematic name 2'-(5-triphosphoribosyl)-3'-dephospho-CoA:apo-malonate-decarboxylase 2'-(5-phosphoribosyl)-3'-dephospho-CoA-transferase .[1][2] This enzyme catalyses the following chemical reaction

Malonate decarboxylase holo-(acyl-carrier protein) synthase
Identifiers
EC no.2.7.7.66
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IntEnzIntEnz view
BRENDABRENDA entry
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NCBIproteins
2'-(5-triphosphoribosyl)-3'-dephospho-CoA + malonate decarboxylase apo-[acyl-carrier protein] malonate decarboxylase holo-[acyl-carrier protein] + diphosphate

The delta subunit of malonate decarboxylase serves as an acyl-carrier protein (ACP) .

References

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  1. ^ Hoenke S, Wild MR, Dimroth P (October 2000). "Biosynthesis of triphosphoribosyl-dephospho-coenzyme A, the precursor of the prosthetic group of malonate decarboxylase". Biochemistry. 39 (43): 13223–32. doi:10.1021/bi0011532. PMID 11052675.
  2. ^ Hoenke S, Schmid M, Dimroth P (October 2000). "Identification of the active site of phosphoribosyl-dephospho-coenzyme A transferase and relationship of the enzyme to an ancient class of nucleotidyltransferases". Biochemistry. 39 (43): 13233–40. doi:10.1021/bi001154u. PMID 11052676.
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