Malonate decarboxylase holo-(acyl-carrier protein) synthase (EC 2.7.7.66, holo ACP synthase, '2'-(5''-triphosphoribosyl)-3'-dephospho-CoA:apo ACP 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA transferase, MdcG, 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA:apo-malonate-decarboxylase adenylyltransferase, holo-malonate-decarboxylase synthase) is an enzyme with systematic name 2'-(5-triphosphoribosyl)-3'-dephospho-CoA:apo-malonate-decarboxylase 2'-(5-phosphoribosyl)-3'-dephospho-CoA-transferase .[1][2] This enzyme catalyses the following chemical reaction
| Malonate decarboxylase holo-(acyl-carrier protein) synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.7.7.66 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- 2'-(5-triphosphoribosyl)-3'-dephospho-CoA + malonate decarboxylase apo-[acyl-carrier protein] malonate decarboxylase holo-[acyl-carrier protein] + diphosphate
The delta subunit of malonate decarboxylase serves as an acyl-carrier protein (ACP) .
References
edit- ^ Hoenke S, Wild MR, Dimroth P (October 2000). "Biosynthesis of triphosphoribosyl-dephospho-coenzyme A, the precursor of the prosthetic group of malonate decarboxylase". Biochemistry. 39 (43): 13223–32. doi:10.1021/bi0011532. PMID 11052675.
- ^ Hoenke S, Schmid M, Dimroth P (October 2000). "Identification of the active site of phosphoribosyl-dephospho-coenzyme A transferase and relationship of the enzyme to an ancient class of nucleotidyltransferases". Biochemistry. 39 (43): 13233–40. doi:10.1021/bi001154u. PMID 11052676.
External links
edit- Malonate+decarboxylase+holo-(acyl-carrier+protein)+synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)[dead link]
