The enzyme malyl-CoA lyase (EC 4.1.3.24) catalyzes the chemical reaction

malyl-CoA lyase
Identifiers
EC no.4.1.3.24
CAS no.37290-67-8
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IntEnzIntEnz view
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ExPASyNiceZyme view
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MetaCycmetabolic pathway
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(3S)-3-carboxy-3-hydroxypropanoyl-CoA acetyl-CoA + glyoxylate

This enzyme belongs to the family of lyases, specifically the oxo-acid-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is (3S)-3-carboxy-3-hydroxypropanoyl-CoA glyoxylate-lyase (acetyl-CoA-forming). Other names in common use include malyl-coenzyme A lyase, and (3S)-3-carboxy-3-hydroxypropanoyl-CoA glyoxylate-lyase. This enzyme participates in glyoxylate and dicarboxylate metabolism.

References

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  • Tuboi S, Kikuchi G (1965). "Enzymic cleavage of malyl-Coenzyme A into acetyl-Coenzyme A and glyoxylic acid". Biochim. Biophys. Acta. 96: 148–153. doi:10.1016/0005-2787(65)90618-0.