Mapua, Māpua or Mapúa may refer to:
- Mapuá River, a river in the Pará state of north-central Brazil
- Māpua, New Zealand, a small town on the South Island of New Zealand
- Mapúa University, a tertiary institute in Manila, Philippines
- Mapúa Cardinals, varsity teams of the university
- Tomás Mapúa, the first registered Filipino architect and founder of Mapúa University