Matteo Orsini may refer to:
- Matteo Rosso Orsini (1178–1246), Roman senator
- Matteo Rosso Orsini (cardinal) (1262–1305)
- Matteo Orsini (died 1340), Dominican friar and cardinal
- Matteo Orsini (bishop) (died 1512)
This disambiguation page lists articles about people with the same name.
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