Mavacoxib (trade name Trocoxil) is a veterinary drug used to treat pain and inflammation in dogs with degenerative joint disease.[2] It acts as a COX-2 inhibitor.[3]
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| Trade names | Trocoxil |
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| ECHA InfoCard | 100.248.948 |
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| Formula | C16H11F4N3O2S |
| Molar mass | 385.34 g·mol−1 |
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Mavacoxib, along with several other COX-2 selective inhibitors, including celecoxib, valdecoxib, and parecoxib, were discovered by a team at the Searle division of Monsanto led by John Talley.[4][5]
References
edit- ^ "Trocoxil EPAR". European Medicines Agency. 22 September 2008. Retrieved 26 June 2024.
- ^ European Public Assessment Report (EPAR): Trocoxil Archived 17 March 2018 at the Wayback Machine, European Medicines Agency
- ^ Cox SR, Lesman SP, Boucher JF, Krautmann MJ, Hummel BD, Savides M, et al. (October 2010). "The pharmacokinetics of mavacoxib, a long-acting COX-2 inhibitor, in young adult laboratory dogs". Journal of Veterinary Pharmacology and Therapeutics. 33 (5): 461–70. doi:10.1111/j.1365-2885.2010.01165.x. PMID 20840390.
{{cite journal}}: CS1 maint: overridden setting (link) - ^ Langreth R (23 June 2003). "The Chemical Cobbler". Forbes.
{{cite news}}: CS1 maint: overridden setting (link) - ^ "Dr. John Talley: 2001 St. Louis Awardee" (PDF). Chemical Bond. 52 (5). St. Louis Section, American Chemical Society: 2. May 2001. Archived from the original (PDF) on 15 April 2018.
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