Mayor West commonly refers to Adam West, a character in the American animated sitcom Family Guy.
Mayor West may also refer to:
- Henry F. West (1796–1856), former mayor of Indianapolis
- Ben West (1911–1974), former mayor of Nashville
- James E. West (politician) (1951–2006), former mayor of Spokane
- Jason West (born 1977), former mayor of the village of New Paltz