Methionine transaminase

Methionine transaminase (EC 2.6.1.88, methionine-oxo-acid transaminase) is an enzyme with systematic name L-methionine:2-oxo-acid aminotransferase.[1][2][3] This enzyme catalyses the following chemical reaction

Methionine transaminase
Identifiers
EC no.2.6.1.88
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins
L-methionine + 2-oxo carboxylate 2-oxo-4-methylthiobutanoate + L-amino acid

The enzyme is most active with L-methionine.

References

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  1. ^ Heilbronn J, Wilson J, Berger BJ (March 1999). "Tyrosine aminotransferase catalyzes the final step of methionine recycling in Klebsiella pneumoniae". Journal of Bacteriology. 181 (6): 1739–47. PMC 93571. PMID 10074065.
  2. ^ Dolzan M, Johansson K, Roig-Zamboni V, Campanacci V, Tegoni M, Schneider G, Cambillau C (July 2004). "Crystal structure and reactivity of YbdL from Escherichia coli identify a methionine aminotransferase function". FEBS Letters. 571 (1–3): 141–6. doi:10.1016/j.febslet.2004.06.075. PMID 15280032.
  3. ^ Schuster J, Knill T, Reichelt M, Gershenzon J, Binder S (October 2006). "Branched-chain aminotransferase4 is part of the chain elongation pathway in the biosynthesis of methionine-derived glucosinolates in Arabidopsis". The Plant Cell. 18 (10): 2664–79. doi:10.1105/tpc.105.039339. PMC 1626624. PMID 17056707.
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