Methylketobemidone

Methylketobemidone is an opioid analgesic that is an analogue of ketobemidone. It was developed in the 1950s during research into analogues of pethidine and was assessed by the United Nations Office on Drugs and Crime but was not included on the list of drugs under international control, probably because it was not used in medicine or widely available.

Methylketobemidone

Clinical data
ATC code	none
Identifiers
IUPAC name 1-[4-(3-hydroxyphenyl)-1-methylpiperidin-4-yl]ethanone
CAS Number	64058-44-2 Y
PubChem CID	47168
ChemSpider	42930 Y
UNII	2K855U2UGA
CompTox Dashboard (EPA)	DTXSID80214224
Chemical and physical data
Formula	C14H19NO2
Molar mass	233.311 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C(C2(c1cccc(O)c1)CCN(C)CC2)C
InChI InChI=1S/C14H19NO2/c1-11(16)14(6-8-15(2)9-7-14)12-4-3-5-13(17)10-12/h3-5,10,17H,6-9H2,1-2H3 Y Key:RNAGZQQIHXIDQH-UHFFFAOYSA-N Y
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Methylketobemidone is so named because it is the methyl ketone analogue of bemidone (hydroxypethidine). The more commonly used ethyl ketone ("ethylketobemidone") is simply called ketobemidone, as it is the only drug of this family to have been marketed.

Presumably methylketobemidone produces similar effects to ketobemidone and other opioids, such as analgesia and sedation, along with side effects such as nausea, itching, vomiting and respiratory depression which may be harmful or fatal.

References

• UNODC Bulletin on Narcotics 1954