Methylphenyltetrahydropyridine N-monooxygenase (EC 1.13.12.11) is an enzyme with systematic name 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine:oxygen N-oxidoreductase.[1] This enzyme catalyses the following chemical reaction
| Methylphenyltetrahydropyridine N-monooxygenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.13.12.11 | ||||||||
| CAS no. | 37256-73-8 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine + O2 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine N-oxide + methanol
Methylphenyltetrahydropyridine N-monooxygenase is a flavoprotein.
References
edit- ^ Chiba K, Kubota E, Miyakawa T, Kato Y, Ishizaki T (September 1988). "Characterization of hepatic microsomal metabolism as an in vivo detoxication pathway of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice". The Journal of Pharmacology and Experimental Therapeutics. 246 (3): 1108–15. PMID 3262153.
External links
edit- Methylphenyltetrahydropyridine+N-monooxygenase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
