Methylphosphonate synthase (EC 1.13.11.73, mpnS (gene)) is an enzyme with systematic name 2-hydroxyethylphosphonate:O2 1,2-oxidoreductase (methylphosphonate forming).[1] This enzyme catalyses the following chemical reaction
| Methylphosphonate synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.13.11.73 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- 2-hydroxyethylphosphonate + O2 methylphosphonate + HCO3−
Methylphosphonate synthase is isolated from the marine archaeon Nitrosopumilus maritimus.
References
edit- ^ Metcalf WW, Griffin BM, Cicchillo RM, Gao J, Janga SC, Cooke HA, Circello BT, Evans BS, Martens-Habbena W, Stahl DA, van der Donk WA (August 2012). "Synthesis of methylphosphonic acid by marine microbes: a source for methane in the aerobic ocean". Science. 337 (6098): 1104–7. doi:10.1126/science.1219875. PMC 3466329. PMID 22936780.
External links
edit- Methylphosphonate+synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
