miRTarBase [1] is a curated database of MicroRNA-Target Interactions. As a database, miRTarBase has accumulated more than fifty thousand miRNA-target interactions (MTIs), which are collected by manually surveying pertinent literature after data mining of the text systematically to filter research articles related to functional studies of miRNAs. Generally, the collected MTIs are validated experimentally by reporter assay, western blot, microarray and next-generation sequencing experiments. While containing the largest amount of validated MTIs, the miRTarBase provides the most updated collection by comparing with other similar, previously developed databases.
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| Content | |
|---|---|
| Description | Experimentally validated microRNA-target interactions (MTIs). |
| Data types captured | miRNA-target interactions |
| Contact | |
| Research center | National Chiao Tung University |
| Laboratory | Institute of Bioinformatics and Systems Biology |
| Authors | Sheng-Da Hsu |
| Primary citation | Hsu & al. (2011)[1] |
| Release date | 2013 |
| Access | |
| Website | http://mirtarbase.cuhk.edu.cn |
| Download URL | http://mirtarbase.cuhk.edu.cn/php/download.php |
| Miscellaneous | |
| Version | 4.5 |
See also
editReferences
edit- ^ a b Hsu SD, Lin FM, Wu WY, Liang C, Huang WC, Chan WL, Tsai WT, Chen GZ, Lee CJ, Chiu CM, Chien CH, Wu MC, Huang CY, Tsou AP, Huang HD (2011). "miRTarBase: a database curates experimentally validated microRNA-target interactions". Nucleic Acids Research. 39 (Database issue): D163-9. doi:10.1093/nar/gkq1107. PMC 3013699. PMID 21071411.
External links
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