Michael Conrad (biologist)

Michael Earl Conrad (1941–2000) was an American theoretical biologist.[1] He was a professor of computer science at Wayne State University.[2] His book Adaptability (1983) has been very influential in theoretical biology.[3]

Michael Conrad
Born1941
Died2000
NationalityAmerican
Scientific career
Fields
  • Theoretical biology
  • Computer science
InstitutionsWayne State University

Conrad was the first to publish theory on the evolution of evolvability, beginning in 1972,[4] with the idea that mutations which smoothed the adaptive landscape would increase the chance that other adaptive mutations could be continually produced, and would thereby hitchhike along with those mutations, thus "bootstrapping the adaptive landscape"[5] to produce the "self-facilitation of evolution".[6]

Career

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Conrad received his A.B. in Biology at Harvard University in 1964. He entered Stanford University Medical School but was persuaded by faculty there to pursue a Ph.D. in Biophysics with Professor Howard H. Pattee, which he obtained in 1969.

Conrad continued with postdoctoral research at the Center for Theoretical Studies at the University of Miami, and the Department of Mathematics at the University of California at Berkeley working with Hans Bremermann. Not finding theoretical biology positions in the United States, Conrad took an Assistant Professorship at the new Institute for Information Processing at the University of Tubingen in 1973, and a temporary position with the Logic of Computers group in the Department of Computer Science and Communication at the University of Michigan at Ann Arbor.

Conrad finally obtained a tenure-track position in the Computer Science department of Wayne State University in 1979, where he remained for the rest of his career.[7]

References

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  1. ^ Obituary in IEEE Transactions on Evolutionary Computation 5(1), 2001.
  2. ^ Obituary in Stanford Magazine
  3. ^ Robert Rosen 1986. [Review.] Bulletin of Mathematical Biology 48(5/6): 701–703.
  4. ^ Conrad, Michael (1972). C.H. Waddington (ed.). "The importance of molecular hierarchy in information processing". Towards a Theoretical Biology. 4. Edinburgh University Press Edinburgh: 222.
  5. ^ Conrad, Michael (1979). "Bootstrapping on the adaptive landscape". BioSystems. 11 (2–3): 167–182. doi:10.1016/0303-2647(79)90009-1. hdl:2027.42/23514. PMID 497367.
  6. ^ Conrad, Michael and Volkenstein, MV (1981). "Replaceability of amino acids and the self-facilitation of evolution". Journal of Theoretical Biology. 92 (3). Elsevier: 293–299. Bibcode:1981JThBi..92..293C. doi:10.1016/0022-5193(81)90293-9. PMID 7329083.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  7. ^ Pattee, Howard (2002). "The origins of Michael Conrad's research programs (1964–1979)". BioSystems. 64 (1–3): 5–11. doi:10.1016/S0303-2647(01)00169-1. PMID 11755483.