Michel Bouvier (born September 14, 1958) is a Canadian biochemist and molecular pharmacologist. He is a professor of biochemistry and molecular medicine at Université de Montréal; a principal investigator and the chief executive officer at the Institute for Research in Immunology and Cancer; and an associate vice-president in Research, Scientific Discovery, Creation, and Innovation at Université de Montréal. His work focuses on the study of cell signaling towards the discovery of new pharmaceutical drugs.[3]
Michel Bouvier | |
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Born | September 14, 1958 |
Citizenship | Canadian |
Awards | Fellow of the Academy of Science of the Royal Society of Canada[1]/ Fellow of the Canadian Academy of Health Sciences / Canada Research Chair in Signal Transduction and Molecular Pharmacology[2] |
Scientific career | |
Fields | Biochemistry and molecular pharmacology |
Biography
editMichel Bouvier earned a B.Sc. in biochemistry (1979) and a Ph.D. in neurological sciences (1985) from Université de Montréal, and then completed a postdoctoral fellowship (1985-1989) at Duke University under the supervision of Robert Lefkowitz (2012 Nobel Prize in Chemistry[4]). Bouvier is a professor in the Department of Biochemistry and Molecular Medicine at the Faculty of Medicine of Université de Montréal and a principal investigator at the Institute for Research in Immunology and Cancer at Université de Montréal.[5]
Research
editHe is a world-known expert[6][7] in cell signaling and drug discovery, notably in the field of G protein-coupled receptors (GPCRs),[8] which constitute the largest single protein family involved in the transduction of hormonal signals and neurotransmitters. Their physiological significance makes them prime targets in drug development, and over a third of existing drugs use GPCRs as their target site of action. Bouvier's work in the regulation of receptors led to new paradigms (inverse agonism; pharmacological chaperones; receptor polymerization; and pluridimensionality of signaling), which, coupled with the development of bioluminescence resonance energy transfer-based methods, have a direct impact on drug discovery.[9] He has authored over 260 scientific articles,[10] filed 36 patent applications, and delivered over 400 lectures as a guest lecturer. Bouvier holds the Canada Research Chair in Signal Transduction and Molecular Pharmacology.[11]
Honours
edit- 2021 - Killam Prize in health sciences[12]
- 2017 - Wilder-Penfield Prize[13]
- 2017 - Julius Axelrod pharmacology prize of the American Society for Pharmacology and Experimental Therapeutics[14]
- 2014 - Member of the Royal Society of Canada[15]
- 2011 - Adrien-Pouliot Prize - Association francophone pour le savoir (Acfas)[16]
- 2006 - Léo-Pariseau Prize (Acfas)[17]
- 2005 - Fellow of the Canadian Academy of Health Sciences[18]
References
edit- ^ Michel Bouvier at RSC
- ^ Research Chair
- ^ "Department of Biochemistry and Molecular Medicine, Faculty of Medicine, Université de Montréal (French)". www.biochimie.umontreal.ca.
- ^ "Michel Bouvier | FORCES magazine". www.magazineforces.com. Retrieved 1 March 2016.
- ^ "Department of Biochemistry and Molecular Medicine, Faculty of Medicine, Université de Montréal (French)". www.biochimie.umontreal.ca. Retrieved 2016-03-01.
- ^ "The World's Most Influential Scientific Minds 2014" (PDF). Retrieved 1 March 2016.
- ^ User, Super. "Domain Therapeutics, Université de Montréal, IRICoR and McGill University sign new licensing and partnership agreement on G-Protein Coupled Receptor biosensor technology". Parc d'Innovation de Strasbourg | Eco-parc d'activité en Alsace. Retrieved 2016-03-01.
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has generic name (help) - ^ "Université de Montréal (via noodls) / Michel Bouvier at the helm of IRIC". www.noodls.com. Retrieved 2016-03-01.
- ^ "MICHEL BOUVIER – Canadian Academy of Health Sciences / Académie canadianne des sciences de la santé". cahs-acss.ca. Retrieved 2016-03-01.
- ^ "Michel Bouvier". ResearchGate. Retrieved 2016-03-01.
- ^ Government of Canada, Industry Canada (2012-11-29). "Canada Research Chairs". Retrieved 2016-03-01.
- ^ "Killam Prizes". Killam Program | Building Canada's Future through Research. Retrieved 2021-02-03.
- ^ "Prix du Québec – Prix Wilder-Penfield - Récipiendaire". Les Prix du Québec. Retrieved 2021-02-03.
- ^ "Julius Axelrod Award in Pharmacology". ASPET. Retrieved 2021-02-03.
- ^ "Member Directory | The Royal Society of Canada". rsc-src.ca. Retrieved 2021-02-03.
- ^ "Prix Adrien-Pouliot - Contrer le diabète, l'obésité et le cancer ? Rien de moins !". Le Devoir (in French). October 2011. Retrieved 2021-02-03.
- ^ "Prix Léo-Pariseau - Décrypter les protéines G". Le Devoir (in French). 14 October 2006. Retrieved 2021-02-03.
- ^ "CAHS Fellows Directory – Canadian Academy of Health Sciences". Retrieved 2021-02-03.
External links
edit- Curriculum vitae, Institute for Research in Immunology and Cancer at the Université de Montréal
- Michel Bouvier's lab