Microtubule associated scaffold protein 2

Microtubule associated scaffold protein 2 is a protein that in humans is encoded by the MTUS2 gene.

MTUS2
Identifiers
Aliases	MTUS2, CAZIP, ICIS, KIAA0774, TIP150, microtubule associated tumor suppressor candidate 2, microtubule associated scaffold protein 2
External IDs	MGI: 1915388; HomoloGene: 78141; GeneCards: MTUS2; OMA:MTUS2 - orthologs
Gene location (Human) Chr. Chromosome 13 (human) Band 13q12.3 Start 28,820,339 bp End 29,505,947 bp
Gene location (Mouse) Chr. Chromosome 5 (mouse) Band 5|5 G3 Start 147,894,130 bp End 148,252,875 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right ventricle myocardium of left ventricle apex of heart cardiac muscle tissue of right atrium right auricle Brodmann area 23 ascending aorta primary visual cortex Descending thoracic aorta gonad Top expressed in interventricular septum zygote right ventricle primary oocyte secondary oocyte myocardium of ventricle autonomic nerve plexus left ventricle otolith organ utricle More reference expression data BioGPS n/a
Orthologs Species Human Mouse Entrez 23281 77521 Ensembl ENSG00000132938 ENSMUSG00000029651 UniProt Q5JR59 Q3UHD3 RefSeq (mRNA) NM_001033602 NM_015233 NM_001366650 NM_001366651 NM_001384605 NM_001384606 NM_029920 NM_001359503 NM_001359505 NM_001359511 RefSeq (protein) NP_001028774 NP_056048 NP_001353579 NP_001353580 NP_084196 NP_001346432 NP_001346434 NP_001346440 Location (UCSC) Chr 13: 28.82 – 29.51 Mb Chr 5: 147.89 – 148.25 Mb PubMed search
Wikidata
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Further reading

• Jiang K, Wang J, Liu J, Ward T, Wordeman L, Davidson A, Wang F, Yao X (2009). "TIP150 interacts with and targets MCAK at the microtubule plus ends". EMBO Rep. 10 (8): 857–65. doi:10.1038/embor.2009.94. PMC 2699393. PMID 19543227.
• Du Puy L, Beqqali A, Monshouwer-Kloots J, Haagsman HP, Roelen BA, Passier R (2009). "CAZIP, a novel protein expressed in the developing heart and nervous system". Dev. Dyn. 238 (11): 2903–11. doi:10.1002/dvdy.22107. PMID 19806667. S2CID 30884001.
• Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR (2010). "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score". Mol. Med. 16 (7–8): 247–53. doi:10.2119/molmed.2009.00159. PMC 2896464. PMID 20379614.
• Ward T, Wang M, Liu X, Wang Z, Xia P, Chu Y, Wang X, Liu L, Jiang K, Yu H, Yan M, Wang J, Hill DL, Huang Y, Zhu T, Yao X (2013). "Regulation of a dynamic interaction between two microtubule-binding proteins, EB1 and TIP150, by the mitotic p300/CBP-associated factor (PCAF) orchestrates kinetochore microtubule plasticity and chromosome stability during mitosis". J. Biol. Chem. 288 (22): 15771–85. doi:10.1074/jbc.M112.448886. PMC 3668735. PMID 23595990.
• Xia P, Zhou J, Song X, Wu B, Liu X, Li D, Zhang S, Wang Z, Yu H, Ward T, Zhang J, Li Y, Wang X, Chen Y, Guo Z, Yao X (2014). "Aurora A orchestrates entosis by regulating a dynamic MCAK-TIP150 interaction". J Mol Cell Biol. 6 (3): 240–54. doi:10.1093/jmcb/mju016. PMC 4034728. PMID 24847103.