Minus-end-directed kinesin ATPase (EC 3.6.4.5) is an enzyme with systematic name kinesin ATP phosphohydrolase (minus-end-directed).[1][2][3] This enzyme catalyses the following chemical reaction
| Minus-end-directed kinesin ATPase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.6.4.5 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- ATP + H2O ADP + phosphate
This enzyme catalyses movement towards the minus end of microtubules.
See also
editReferences
edit- ^ Henningsen U, Schliwa M (September 1997). "Reversal in the direction of movement of a molecular motor". Nature. 389 (6646): 93–6. doi:10.1038/38022. PMID 9288974.
- ^ Sharp DJ, Kuriyama R, Essner R, Baas PW (October 1997). "Expression of a minus-end-directed motor protein induces Sf9 cells to form axon-like processes with uniform microtubule polarity orientation". Journal of Cell Science. 110 ( Pt 19): 2373–80. PMID 9410876.
- ^ Sablin EP, Case RB, Dai SC, Hart CL, Ruby A, Vale RD, Fletterick RJ (October 1998). "Direction determination in the minus-end-directed kinesin motor ncd". Nature. 395 (6704): 813–6. doi:10.1038/27463. PMID 9796817.
External links
edit- Minus-end-directed+kinesin+ATPase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
