mir-25 microRNA precursor family

In molecular biology mir-25 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms. mir-25 levels increase in human heart failure, and treatment with an anti-sense RNA molecule (antagomiR) was recently reported to halt disease progression and improves cardiac function in a mouse heart failure model.[1]

mir-25
Identifiers
Symbolmir-25
RfamRF02020
miRBase family25
Other data
RNA typemicroRNA
Domain(s)Eukaryota;
PDB structuresPDBe

See also

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References

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  1. ^ Wahlquist C, Jeong D, Rojas-Muñoz A, Kho C, Lee A, Mitsuyama S, van Mil A, Park WJ, Sluijter JP, Doevendans PA, Hajjar RJ, Mercola M (April 2014). "Inhibition of miR-25 improves cardiac contractility in the failing heart". Nature. 508 (7497): 531–5. doi:10.1038/nature13073. PMC 4131725. PMID 24670661.

Further reading

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