mir-395 is a non-coding RNA called a microRNA that was identified in both Arabidopsis thaliana and Oryza sativa computationally and was later experimentally verified. mir-395 is thought to target mRNAs coding for ATP sulphurylases.[1] The mature sequence is excised from the 3' arm of the hairpin.
| mir-395 microRNA precursor family | |
|---|---|
 Predicted secondary structure and sequence conservation of mir-395 | |
| Identifiers | |
| Symbol | mir-395 |
| Rfam | RF00451 |
| miRBase | MI0001007 |
| miRBase family | MIPF0000016 |
| Other data | |
| RNA type | Gene; miRNA |
| Domain(s) | Eukaryota |
| GO | GO:0035195 GO:0035068 |
| SO | SO:0001244 |
| PDB structures | PDBe |
miR-395 is upregulated in Arabidopsis during sulphate-limited conditions, when the mature miRNA then regulates sulphur transporters and ATP sulphurylases.[2][3]
References
edit- ^ Jones-Rhoades MW, Bartel DP (June 2004). "Computational identification of plant microRNAs and their targets, including a stress-induced miRNA". Molecular Cell. 14 (6): 787–99. doi:10.1016/j.molcel.2004.05.027. PMID 15200956.
- ^ Liang G, Yang F, Yu D (June 2010). "MicroRNA395 mediates regulation of sulfate accumulation and allocation in Arabidopsis thaliana". The Plant Journal. 62 (6): 1046–57. doi:10.1111/j.1365-313X.2010.04216.x. PMID 20374528.
- ^ Liang G, Yu D (October 2010). "Reciprocal regulation among miR395, APS and SULTR2;1 in Arabidopsis thaliana". Plant Signaling & Behavior. 5 (10): 1257–9. doi:10.4161/psb.5.10.12608. PMC 3115361. PMID 20935495.
External links
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