Misaka is a surname. Notable people and fictional characters with the name include:
People
edit- Wat Misaka (1923–2019), American basketball player
Fictional characters
edit- Kaori Misaka, a character in the Kanon series
- Mikoto Misaka, one of the main characters in the A Certain Magical Index series
- Shiori Misaka, a character in the Kanon series