Mitu is a Romanian surname. Notable people with the surname include:
- Andreea Mitu (born 1991), Romanian tennis player
- Dumitru Mitu (born 1975), Romanian former footballer
- Gogea Mitu (1914–1936), Romanian boxer
- Marius Mitu (born 1976), Romanian footballer
- Petre Mitu (born 1977), Romanian rugby union player