Mohammed Usman may refer to:
- Mohammed Usman (general), Nigerian general
- Mohammed Usman (footballer, born 1980), Nigerian footballer for Kwara United F.C.
- Mohammed Usman (footballer, born 1994), Nigerian footballer for Sarpsborg 08
- Mohammed Usman (MMA Fighter, Born 1989), Nigerian Heavyweight UFC Fighter
- Muhammed Usman Edu (born 1994), Nigerian footballer