Mollien is a surname. Notable people with the surname include:
- André Mollien (1906-1952), Swiss bobsledder
- Félix Ravaisson-Mollien (1813-1900), French philosopher
- Gaspard Théodore Mollien (1796-1872), a French diplomat and explorer
- Jean Mollien (1903-1952), Swiss bobsledder
- Nicolas François, Count Mollien (1758-1850), a French financier