Molybdenum cofactor sulfurtransferase

Molybdenum cofactor sulfurtransferase (EC 2.8.1.9, molybdenum cofactor sulfurase, ABA3, MoCo sulfurase, MoCo sulfurtransferase) is an enzyme with systematic name L-cysteine:molybdenum cofactor sulfurtransferase.[1][2][3] This enzyme catalyses the following chemical reaction

Molybdenum cofactor sulfurtransferase
Identifiers
EC no.2.8.1.9
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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NCBIproteins
molybdenum cofactor + L-cysteine + 2 H+ thio-molybdenum cofactor + L-alanine + H2O

This enzyme contains pyridoxal phosphate.

References

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  1. ^ Bittner F, Oreb M, Mendel RR (November 2001). "ABA3 is a molybdenum cofactor sulfurase required for activation of aldehyde oxidase and xanthine dehydrogenase in Arabidopsis thaliana". The Journal of Biological Chemistry. 276 (44): 40381–4. doi:10.1074/jbc.c100472200. PMID 11553608.
  2. ^ Heidenreich T, Wollers S, Mendel RR, Bittner F (February 2005). "Characterization of the NifS-like domain of ABA3 from Arabidopsis thaliana provides insight into the mechanism of molybdenum cofactor sulfuration". The Journal of Biological Chemistry. 280 (6): 4213–8. doi:10.1074/jbc.m411195200. PMID 15561708.
  3. ^ Wollers S, Heidenreich T, Zarepour M, Zachmann D, Kraft C, Zhao Y, Mendel RR, Bittner F (April 2008). "Binding of sulfurated molybdenum cofactor to the C-terminal domain of ABA3 from Arabidopsis thaliana provides insight into the mechanism of molybdenum cofactor sulfuration". The Journal of Biological Chemistry. 283 (15): 9642–50. doi:10.1074/jbc.m708549200. PMID 18258600.
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