Mt-rnr2-like 1

MT-RNR2-like 1 is a protein that in humans is encoded by the MTRNR2L1 gene.

MTRNR2L1
Identifiers
Aliases	MTRNR2L1, HN1, MT-RNR2-like 1, MT-RNR2 like 1, MT-RNR2 like 1 (pseudogene)
External IDs	OMIM: 616985; GeneCards: MTRNR2L1; OMA:MTRNR2L1 - orthologs
Gene location (Human) Chr. Chromosome 17 (human) Band 17p11.2 Start 22,523,415 bp End 22,524,663 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sural nerve stomach brain colon heart substantia nigra muscle tissue Cerebellum testicle prefrontal cortex n/a More reference expression data BioGPS n/a
Gene ontology Molecular function receptor antagonist activity Cellular component cytoplasm extracellular region Biological process extracellular negative regulation of signal transduction negative regulation of execution phase of apoptosis negative regulation of signaling receptor activity Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 100462977 n/a Ensembl ENSG00000256618 n/a UniProt P0CJ68 n/a RefSeq (mRNA) NM_001190452 n/a RefSeq (protein) NP_001177381 n/a Location (UCSC) Chr 17: 22.52 – 22.52 Mb n/a PubMed search n/a
Wikidata
View/Edit Human

Further reading

• Moretti E, Giannerini V, Rossini L, Matsuoka M, Trabalzini L, Collodel G (2010). "Immunolocalization of humanin in human sperm and testis". Fertil. Steril. 94 (7): 2888–90. doi:10.1016/j.fertnstert.2010.04.075. PMID 20542501.
• Zhao ST, Huang XT, Zhang C, Ke Y (2012). "Humanin protects cortical neurons from ischemia and reperfusion injury by the increased activity of superoxide dismutase". Neurochem. Res. 37 (1): 153–60. doi:10.1007/s11064-011-0593-0. PMID 21935731. S2CID 16248228.
• Zapała B, Staszel T, Kieć-Wilk B, Polus A, Knapp A, Wybrańska I, Kaczyński Ł, Dembińska-Kieć A (2011). "[Humanin and its derivatives as peptides with potential antiapoptotic and confirmed neuroprotective activities]". Prz. Lek. (in Polish). 68 (7): 372–7. PMID 22010475.
• Lee C, Yen K, Cohen P (2013). "Humanin: a harbinger of mitochondrial-derived peptides?". Trends Endocrinol. Metab. 24 (5): 222–8. doi:10.1016/j.tem.2013.01.005. PMC 3641182. PMID 23402768.