Mycoredoxin (EC 1.20.4.3, Mrx1, MrxI) is an enzyme with systematic name arseno-mycothiol:mycoredoxin oxidoreductase.[1] This enzyme catalyses the following chemical reaction
| Mycoredoxin | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.20.4.3 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- arseno-mycothiol + mycoredoxin arsenite + mycothiol-mycoredoxin disulfide
Reduction of arsenate is part of a defense mechanism of the cell against toxic arsenate.
References
edit- ^ Ordóñez E, Van Belle K, Roos G, De Galan S, Letek M, Gil JA, Wyns L, Mateos LM, Messens J (May 2009). "Arsenate reductase, mycothiol, and mycoredoxin concert thiol/disulfide exchange". The Journal of Biological Chemistry. 284 (22): 15107–16. doi:10.1074/jbc.m900877200. PMC 2685692. PMID 19286650.
External links
edit- Mycoredoxin at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
