N-Ethylbuphedrone

N-Ethylbuphedrone
Legal status
Legal status	DE: Anlage I (Authorized scientific use only); UK: Class B;
Identifiers
	IUPAC name 2-(Ethylamino)-1-phenylbutan-1-one;
CAS Number	1354631-28-9;
PubChem CID	20326296;
ChemSpider	15397161;
UNII	VUF6VC063Q;
CompTox Dashboard (EPA)	DTXSID30605441 ;
Chemical and physical data
Formula	C12H17NO
Molar mass	191.274 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCNC(CC)C(=O)c1ccccc1;
	InChI InChI=1S/C12H17NO/c1-3-11(13-4-2)12(14)10-8-6-5-7-9-10/h5-9,11,13H,3-4H2,1-2H3; Key:HEPVRDHGUWFXJS-UHFFFAOYSA-N;

N-Ethylbuphedrone (also known as NEB) is a stimulant of the cathinone class that has been sold as a designer drug.^[1]^[2]^[3]^[4] It is the β-ketone analogue of N,alpha-diethylphenylethylamine.

Legal status

As of October 2015 NEB is a controlled substance in China.^[5]

In the United States NEB is considered a schedule 1 controlled substance as a positional isomer of 4-Methylethcathinone (4-MEC) ^[6]

References

^ Lanza M, Acton WJ, Jürschik S, Sulzer P, Breiev K, Jordan A, et al. (September 2013). "Distinguishing two isomeric mephedrone substitutes with selective reagent ionisation mass spectrometry (SRI-MS)". Journal of Mass Spectrometry. 48 (9): 1015–1018. Bibcode:2013JMSp...48.1015L. doi:10.1002/jms.3253. PMID 24078242.
^ Acton WJ, Lanza M, Agarwal B, Jürschik S, Sulzer P, Breiev K, et al. (March 2014). "Headspace analysis of new psychoactive substances using a Selective Reagent Ionisation-Time of Flight-Mass Spectrometer". International Journal of Mass Spectrometry. 360: 28–38. Bibcode:2014IJMSp.360...28A. doi:10.1016/j.ijms.2013.12.009. PMC 4375562. PMID 25844048.
^ Uralets V, Rana S, Morgan S, Ross W (June 2014). "Testing for designer stimulants: metabolic profiles of 16 synthetic cathinones excreted free in human urine". Journal of Analytical Toxicology. 38 (5): 233–241. doi:10.1093/jat/bku021. PMID 24668489.
^ Pieprzyca E, Skowronek R, Czekaj P (November 2021). "Toxicological Analysis of Cases of Mixed Poisonings with Synthetic Cathinones and other Drugs of Abuse". Journal of Analytical Toxicology. 46 (9): 1008–1015. doi:10.1093/jat/bkab119. PMID 34849994.
^ "关于印发《非药用类麻醉药品和精神药品列管办法》的通知" (in Chinese). China Food and Drug Administration. 27 September 2015. Archived from the original on 1 October 2015. Retrieved 1 October 2015.
^ Diversion Control Division (February 2023). Lists of: Scheduling Actions; Controlled Substances; Regulated Chemicals (PDF) (Report). U.S. Department of Justice, Drug Enforcement Administration. Archived (PDF) from the original on 2023-03-06.

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[1] Lanza M, Acton WJ, Jürschik S, Sulzer P, Breiev K, Jordan A, et al. (September 2013). "Distinguishing two isomeric mephedrone substitutes with selective reagent ionisation mass spectrometry (SRI-MS)". Journal of Mass Spectrometry. 48 (9): 1015–1018. Bibcode:2013JMSp...48.1015L. doi:10.1002/jms.3253. PMID 24078242.

[2] Acton WJ, Lanza M, Agarwal B, Jürschik S, Sulzer P, Breiev K, et al. (March 2014). "Headspace analysis of new psychoactive substances using a Selective Reagent Ionisation-Time of Flight-Mass Spectrometer". International Journal of Mass Spectrometry. 360: 28–38. Bibcode:2014IJMSp.360...28A. doi:10.1016/j.ijms.2013.12.009. PMC 4375562. PMID 25844048.

[3] Uralets V, Rana S, Morgan S, Ross W (June 2014). "Testing for designer stimulants: metabolic profiles of 16 synthetic cathinones excreted free in human urine". Journal of Analytical Toxicology. 38 (5): 233–241. doi:10.1093/jat/bku021. PMID 24668489.

[4] Pieprzyca E, Skowronek R, Czekaj P (November 2021). "Toxicological Analysis of Cases of Mixed Poisonings with Synthetic Cathinones and other Drugs of Abuse". Journal of Analytical Toxicology. 46 (9): 1008–1015. doi:10.1093/jat/bkab119. PMID 34849994.

[5] "关于印发《非药用类麻醉药品和精神药品列管办法》的通知" (in Chinese). China Food and Drug Administration. 27 September 2015. Archived from the original on 1 October 2015. Retrieved 1 October 2015.

[6] Diversion Control Division (February 2023). Lists of: Scheduling Actions; Controlled Substances; Regulated Chemicals (PDF) (Report). U.S. Department of Justice, Drug Enforcement Administration. Archived (PDF) from the original on 2023-03-06.

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N-Ethylbuphedrone

Legal status

See also

References