N-Formylmorpholine is the organic compound with the formula O(C2H4)2NCHO. It is the formamide of morpholine (O(C2H4)2NH). A colorless compound, it is a useful high temperature solvent akin to dimethylformamide.[1] It has been used as a formylating agent.[2]
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| Names | |
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| Preferred IUPAC name
Morpholine-4-carbaldehyde | |
| Other names
Formylmorpholine
4-Morpholinecarboxaldehyde | |
| Identifiers | |
3D model (JSmol)
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| ECHA InfoCard | 100.022.291 |
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PubChem CID
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| UNII | |
CompTox Dashboard (EPA)
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| Properties | |
| C5H9NO2 | |
| Molar mass | 115.132 g·mol−1 |
| Appearance | Colorless or white solid |
| Density | 1.145 gm/cm3 (26 °C) |
| Melting point | 21 °C (70 °F; 294 K) |
| Boiling point | 239 °C (462 °F; 512 K) |
| Hazards | |
| GHS labelling: | |
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| Warning | |
| H317, H319, H335 | |
| P261, P264, P271, P272, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P333+P313, P337+P313, P363, P403+P233, P405, P501 | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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References
edit- ^ Bipp, H.; Kieczka, H. (2012). "Formamides". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi:10.1002/14356007.a12_001.pub2. ISBN 978-3527306732.
- ^ George A. Olah; Lena Ohannesian; Massoud Arvanaghi (1984). "N-Formylmorpholine: a New and Effective Formylating Agent for the Preparation of Aldehydes and Dialkyl (1-formylalkyl)phosphonates from Grignard or Organolithium Reagents". J. Org. Chem. 49: 3856–3857. doi:10.1021/jo00194a045.