N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase (EC 2.4.1.141, UDP-GlcNAc:dolichyl-pyrophosphoryl-GlcNAc GlcNAc transferase, uridine diphosphoacetylglucosamine-dolichylacetylglucosamine pyrophosphate acetylglucosaminyltransferase, N,N'-diacetylchitobiosylpyrophosphoryldolichol synthase) is an enzyme with systematic name UDP-N-acetyl-D-glucosamine:N-acetyl-D-glucosaminyl-diphosphodolichol N-acetyl-D-glucosaminyltransferase.[1][2] This enzyme catalyses the following chemical reaction
| N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.4.1.141 | ||||||||
| CAS no. | 75536-54-8 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- UDP-N-acetyl-D-glucosamine + N-acetyl-D-glucosaminyl-diphosphodolichol UDP + N,N'-diacetylchitobiosyl-diphosphodolichol
References
edit- ^ Sharma CB, Lehle L, Tanner W (August 1982). "Solubilization and characterization of the initial enzymes of the dolichol pathway from yeast". European Journal of Biochemistry. 126 (2): 319–25. doi:10.1111/j.1432-1033.1982.tb06781.x. PMID 6215245.
- ^ Turco SJ, Heath EC (May 1977). "Glucuronosyl-N-acetylglucosaminyl pyrophosphoryldolichol. Formation in SV40-transformed human lung fibroblasts and biosynthesis in rat lung microsomal preparations". The Journal of Biological Chemistry. 252 (9): 2918–28. PMID 192724.
External links
edit- N-acetylglucosaminyldiphosphodolichol+N-acetylglucosaminyltransferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
