N-methylphosphoethanolamine cytidylyltransferase

In enzymology, a N-methylphosphoethanolamine cytidylyltransferase (EC 2.7.7.57) is an enzyme that catalyzes the chemical reaction

N-methylphosphoethanolamine cytidylyltransferase
Identifiers
EC no.2.7.7.57
CAS no.119345-28-7
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins
CTP + N-methylethanolamine phosphate diphosphate + CDP-N-methylethanolamine

Thus, the two substrates of this enzyme are CTP and N-methylethanolamine phosphate, whereas its two products are diphosphate and CDP-N-methylethanolamine.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is CTP:N-methylethanolamine-phosphate cytidylyltransferase. Other names in common use include monomethylethanolamine phosphate cytidylyltransferase, and CTP:P-MEA cytidylyltransferase.

References

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  • Datko AH, Mudd SH (December 1988). "Enzymes of phosphatidylcholine synthesis in lemna, soybean, and carrot". Plant Physiology. 88 (4): 1338–48. doi:10.1104/pp.88.4.1338. PMC 1055762. PMID 16666464.