N4-(beta-N-acetylglucosaminyl)-L-asparaginase (EC 3.5.1.26, aspartylglucosylamine deaspartylase, aspartylglucosylaminase, aspartylglucosaminidase, aspartylglycosylamine amidohydrolase, N-aspartyl-beta-glucosaminidase, glucosylamidase, beta-aspartylglucosylamine amidohydrolase, 4-N-(beta-N-acetyl-D-glucosaminyl)-L-asparagine amidohydrolase) is an enzyme with systematic name N4-(beta-N-acetyl-D-glucosaminyl)-L-asparagine amidohydrolase.[1][2][3] This enzyme catalyses the following chemical reaction
| N4-(beta-N-acetylglucosaminyl)-L-asparaginase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.5.1.26 | ||||||||
| CAS no. | 9075-24-5 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- N4-(beta-N-acetyl-D-glucosaminyl)-L-asparagine + H2O N-acetyl-beta-D-glucosaminylamine + L-aspartate
This enzyme acts only on asparagine-oligosaccharides containing one amino acid.
See also
editReferences
edit- ^ Kono M, Yamashina I (February 1972). "Purification and properties of 4-L-aspartylglycosylamine amidohydrolase from hog kidney". Biochimica et Biophysica Acta (BBA) - Enzymology. 258 (2): 600–17. doi:10.1016/0005-2744(72)90252-5. PMID 5010303.
- ^ Mahadevan S, Tappel AL (October 1967). "Beta-aspartylglucosylamine amido hydrolase of rat liver and kidney". The Journal of Biological Chemistry. 242 (20): 4568–76. doi:10.1016/S0021-9258(18)99494-9. PMID 6061403.
- ^ Tarentino AL, Maley F (March 1969). "The purification and properties of a beta-aspartyl N-acetylglucosylamine amidohydrolase from hen oviduct". Archives of Biochemistry and Biophysics. 130 (1): 295–303. doi:10.1016/0003-9861(69)90036-8. PMID 5778645.
External links
edit- N4-(beta-N-acetylglucosaminyl)-L-asparaginase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
 | This enzyme-related article is a stub. You can help Wikipedia by expanding it. |