Neuronal growth regulator 1 also known as NEGR1 is a protein which in humans is encoded by the NEGR1 gene .[ 5]
Clinical significance
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Variants of the NEGR1 gene may be associated with obesity and major depression.[ 6] [ 7] [ 8]
^ a b c GRCh38: Ensembl release 89: ENSG00000172260 – Ensembl , May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000040037 – Ensembl , May 2017
^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
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^ Thorleifsson G, Walters GB, Gudbjartsson DF, et al. (January 2009). "Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity". Nat. Genet . 41 (1): 18–24. doi :10.1038/ng.274 . PMID 19079260 . S2CID 764409 .
^ Willer CJ, Speliotes EK, Loos RJ, et al. (January 2009). "Six new loci associated with body mass index highlight a neuronal influence on body weight regulation" . Nat. Genet . 41 (1): 24–34. doi :10.1038/ng.287 . PMC 2695662 . PMID 19079261 .
^ Zhao J, Bradfield JP, Li M, et al. (May 2009). "The role of obesity-associated loci identified in genome wide association studies in the determination of pediatric BMI" . Obesity (Silver Spring) . 17 (12): 2254–7. doi :10.1038/oby.2009.159 . PMC 2860782 . PMID 19478790 .
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