NS102 is a kainate receptor antagonist.[2][3]
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IUPAC name
5-Nitro-6,7,8,9-tetrahydro-1H-benzo[g]indole-2,3-dione 3-oxime
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Identifiers | |
3D model (JSmol)
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ChemSpider | |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C12H11N3O4 | |
Molar mass | 261.237 g·mol−1 |
Appearance | Yellow solid |
Insoluble | |
Solubility in DMSO | >3 mg/mL |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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References
edit- ^ NS102 at Sigma-Aldrich
- ^ Johansen, Tina H; Drejer, Joergen; Watjen, Frank; Nielsen, Elsebet O (1993). "A novel non-NMDA receptor antagonist shows selective displacement of low-affinity [3H]kainate binding". European Journal of Pharmacology. 246 (3): 195–204. doi:10.1016/0922-4106(93)90031-4. PMID 8223944.
- ^ Dev KK, Petersen V, Honoré T, Henley JM (1996). "Pharmacology and regional distribution of the binding of 6-[3H]nitro-7-sulphamoylbenzo[f]-quinoxaline-2,3-dione to rat brain". J. Neurochem. 67 (6): 2609–12. doi:10.1046/j.1471-4159.1996.67062609.x. PMID 8931496. S2CID 39382212.