Nafadotride is a dopamine antagonist with some selectivity for the D3 subtype (9.6-fold preference for D3 over D2).[1]
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IUPAC name
N-{[(2S)-1-butylpyrrolidin-2-yl]methyl}-4-cyano-1-methoxy-2-naphthamide
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Identifiers | |
3D model (JSmol)
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ChEMBL | |
MeSH | Nafadotride |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C22H27N3O2 | |
Molar mass | 365.477 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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See also
editReferences
edit- ^ Pilla M, Perachon S, Sautel F, Garrido F, Mann A, Wermuth CG, Schwartz JC, Everitt BJ, Sokoloff P. Selective inhibition of cocaine-seeking behaviour by a partial dopamine D3 agonist. Nature. 1999;400:371–375.