Nicotinate dehydrogenase (cytochrome)

Nicotinate dehydrogenase (cytochrome) (EC 1.17.2.1, nicotinic acid hydroxylase, nicotinate hydroxylase) is an enzyme with systematic name nicotinate:cytochrome 6-oxidoreductase (hydroxylating).[1][2] This enzyme catalyses the following chemical reaction

Nicotinate dehydrogenase (cytochrome)
Identifiers
EC no.1.17.2.1
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins
nicotinate + a ferricytochrome + H2O 6-hydroxynicotinate + a ferrocytochrome + 2 H+

This two-component enzyme from Pseudomonas belongs to the family of xanthine dehydrogenases.

See also

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References

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  1. ^ Jiménez JI, Canales A, Jiménez-Barbero J, Ginalski K, Rychlewski L, García JL, Díaz E (August 2008). "Deciphering the genetic determinants for aerobic nicotinic acid degradation: the nic cluster from Pseudomonas putida KT2440". Proceedings of the National Academy of Sciences of the United States of America. 105 (32): 11329–34. doi:10.1073/pnas.0802273105. PMC 2516282. PMID 18678916.
  2. ^ Yang Y, Yuan S, Chen T, Ma P, Shang G, Dai Y (July 2009). "Cloning, heterologous expression, and functional characterization of the nicotinate dehydrogenase gene from Pseudomonas putida KT2440". Biodegradation. 20 (4): 541–9. doi:10.1007/s10532-008-9243-x. PMID 19118407. S2CID 23219659.
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