Nigrosporin B is a naphthoquinone isolate of the fungus Nigrospora. Nigrosporin B has anti-mycobacterial activity.[1]

Nigrosporin B
Names
Preferred IUPAC name
(6R,7S)-6,7,10-Trihydroxy-2-methoxy-7-methyl-5,6,7,8-tetrahydroanthracene-1,4-dione
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
  • InChI=1S/C16H16O6/c1-16(21)6-7-3-9-13(15(20)8(7)4-12(16)18)10(17)5-11(22-2)14(9)19/h3,5,12,18,20-21H,4,6H2,1-2H3/t12-,16+/m1/s1
    Key: QNFWEYHUDXOXHJ-WBMJQRKESA-N
  • InChI=1/C16H16O6/c1-16(21)6-7-3-9-13(15(20)8(7)4-12(16)18)10(17)5-11(22-2)14(9)19/h3,5,12,18,20-21H,4,6H2,1-2H3/t12-,16+/m1/s1
    Key: QNFWEYHUDXOXHJ-WBMJQRKEBZ
  • C[C@@]1(CC2=C(C[C@H]1O)C(=C3C(=C2)C(=O)C(=CC3=O)OC)O)O
Properties
C16H16O6
Molar mass 304.298 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Notes

edit
  1. ^ Wang C, Wang J, Huang Y, Chen H, Li Y, Zhong L, et al. (2013). "Anti-mycobacterial activity of marine fungus-derived 4-deoxybostrycin and nigrosporin". Molecules. 18 (2): 1728–40. doi:10.3390/molecules18021728. PMC 6269944. PMID 23434859.