Nikodim is a masculine given name which may refer to:
- Saint Nikodim I (died 1325), Eastern Orthodox saint, 10th Metropolitan of Peć and Archbishop of the Serbs
- Metropolitan Nikodim (Rotov) of Leningrad (1929–1978), Metropolitan of Leningrad and Minsk, and undercover KGB agent
- Nikodim Milaš (1845–1915), Serbian Orthodox Church bishop