Nucleoside oxidase (EC 1.1.3.28) is an enzyme with systematic name nucleoside:oxygen 5'-oxidoreductase.[1][2] This enzyme catalyses the following chemical reaction
| Nucleoside oxidase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.1.3.28 | ||||||||
| CAS no. | 82599-71-1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- inosine + O2 9-riburonosylhypoxanthine + H2O
- (1a) 2 inosine + O2 2 5'-dehydroinosine + 2 H2O
- (1b) 2 5'-dehydroinosine + O2 2 9-riburonosylhypoxanthine
This enzyme could use other purine and pyrimidine nucleosides (as well as 2'-deoxynucleosides) as substrates.
References
edit- ^ Isono Y, Sudo T, Hoshino M (1989). "Purification and reaction of a new enzyme, nucleoside oxidase". Agric. Biol. Chem. 53: 1663–1669. doi:10.1271/bbb1961.53.1663.
- ^ Isono Y, Sudo T, Hoshino M (1989). "Properties of a new enzyme, nucleoside oxidase, from Pseudomonas maltophilia LB-86". Agric. Biol. Chem. 53: 1671–1677. doi:10.1271/bbb1961.53.1671.
External links
edit- Nucleoside+oxidase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
