OEB may refer to:
- The Official Encyclopedia of Bridge
- Online Educa Berlin, an annual conference on technology-supported learning
- Online Egyptological Bibliography
- Ontario Energy Board, which regulates natural gas and electricity utilities in Ontario
- Open eBook, an e-book format
- Open English Bible, a Bible translation
- Operation Engineering Bulletin, a type of Aircraft flight manual
- KOPB-TV or Oregon Educational Broadcasting, a public television station
- Branch County Memorial Airport's FAA location identifier
- Oil Equivalent Barrel, unit of energy released by burning one barrel of crude oil
- Octavia E. Butler, an American science-fiction author