OR13C8

Olfactory receptor 13C8 is a protein that in humans is encoded by the OR13C8 gene.

OR13C8
Identifiers
Aliases	OR13C8, OR37H, OR9-10, olfactory receptor family 13 subfamily C member 8
External IDs	MGI: 3030106; HomoloGene: 17409; GeneCards: OR13C8; OMA:OR13C8 - orthologs
Gene location (Human) Chr. Chromosome 9 (human) Band 9q31.1 Start 104,569,168 bp End 104,570,130 bp
Gene location (Mouse) Chr. Chromosome 4 (mouse) Band 4|4 B2 Start 52,910,207 bp End 52,919,178 bp
RNA expression pattern Bgee Human Mouse (ortholog) n/a Top expressed in respiratory epithelium peripheral nervous system nasal epithelium olfactory epithelium lens BioGPS More reference expression data
Gene ontology Molecular function olfactory receptor activity signal transducer activity G protein-coupled receptor activity Cellular component membrane integral component of membrane plasma membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 138802 258836 Ensembl ENSG00000186943 ENSMUSG00000051593 UniProt Q8NGS7 Q8VGA0 RefSeq (mRNA) NM_001004483 NM_146839 RefSeq (protein) NP_001004483 NP_667050 Location (UCSC) Chr 9: 104.57 – 104.57 Mb Chr 4: 52.91 – 52.92 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. CiteSeerX 10.1.1.145.6233. doi:10.1006/geno.2002.6830. PMID 12213199.
• Hoppe R, Breer H, Strotmann J (2004). "Organization and evolutionary relatedness of OR37 olfactory receptor genes in mouse and human". Genomics. 82 (3): 355–64. doi:10.1016/S0888-7543(03)00116-2. PMID 12906860.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.
• Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9". Nature. 429 (6990): 369–74. Bibcode:2004Natur.429..369H. doi:10.1038/nature02465. PMC 2734081. PMID 15164053.

External links

• OR13C8+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.