OR13J1

Olfactory receptor 13J1 is a protein that in humans is encoded by the OR13J1 gene.

OR13J1
Identifiers
Aliases	OR13J1, OR9-2, olfactory receptor family 13 subfamily J member 1
External IDs	MGI: 1860080; HomoloGene: 10460; GeneCards: OR13J1; OMA:OR13J1 - orthologs
Gene location (Human) Chr. Chromosome 9 (human) Band 9p13.3 Start 35,869,463 bp End 35,870,401 bp
Gene location (Mouse) Chr. Chromosome 4 (mouse) Band 4|4 A5 Start 43,704,562 bp End 43,710,255 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in prefrontal cortex primary visual cortex anterior cingulate cortex hippocampus proper right frontal lobe superior frontal gyrus putamen dorsolateral prefrontal cortex temporal lobe amygdala Top expressed in intestinal villus Ileal epithelium perirhinal cortex entorhinal cortex choroid plexus of fourth ventricle CA3 field lactiferous gland extraocular muscle medial ganglionic eminence tracheobronchial tree More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 392309 56015 Ensembl ENSG00000168828 ENSMUSG00000046450 UniProt Q8NGT2 Q9QZ18 RefSeq (mRNA) NM_001004487 NM_019486 RefSeq (protein) NP_001004487 NP_062359 Location (UCSC) Chr 9: 35.87 – 35.87 Mb Chr 4: 43.7 – 43.71 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. CiteSeerX 10.1.1.145.6233. doi:10.1006/geno.2002.6830. PMID 12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.
• Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9". Nature. 429 (6990): 369–74. Bibcode:2004Natur.429..369H. doi:10.1038/nature02465. PMC 2734081. PMID 15164053.

External links

• OR13J1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.