Olfactory receptor 2W3 is a protein that in humans is encoded by the OR2W3 gene.[5][6]
| OR2W3 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Aliases | OR2W3, OR2W3P, OR2W8P, OST718, olfactory receptor family 2 subfamily W member 3 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 616729; MGI: 3030156; HomoloGene: 19876; GeneCards: OR2W3; OMA:OR2W3 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[6]
See also
editReferences
edit- ^ a b c GRCh38: Ensembl release 89: ENSG00000238243 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000063549 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Malnic B, Godfrey PA, Buck LB (Feb 2004). "The human olfactory receptor gene family". Proc Natl Acad Sci U S A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.
- ^ a b "Entrez Gene: OR2W3 olfactory receptor, family 2, subfamily W, member 3".
Further reading
edit- Hillier LD, Lennon G, Becker M, et al. (1997). "Generation and analysis of 280,000 human expressed sequence tags". Genome Res. 6 (9): 807–28. doi:10.1101/gr.6.9.807. PMID 8889549.
- Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. CiteSeerX 10.1.1.135.3652. doi:10.1006/geno.2002.6830. PMID 12213199.
External links
edit- OR2W3+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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