Obovatol is a biphenolic anti-inflammatory, anxiolytic, and nootropic isolated from the bark of Magnolia obovata.[1] It is a biphenyl lignan.[2]
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Preferred IUPAC name
5-(Prop-2-en-1-yl)-3-[4-(prop-2-en-1-yl)phenoxy]benzene-1,2-diol | |
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3D model (JSmol)
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ChEMBL | |
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PubChem CID
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CompTox Dashboard (EPA)
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Properties | |
C18H18O3 | |
Molar mass | 282.339 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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References
edit- ^ Choi, DY; Lee, JW; Peng, J; Lee, YJ; Han, JY; Lee, YH; Choi, IS; Han, SB; Jung, JK; Lee, WS; Lee, SH; Kwon, BM; Oh, KW; Hong, JT (2012). "Obovatol improves cognitive functions in animal models for Alzheimer's disease". Journal of Neurochemistry. 120 (6): 1048–59. doi:10.1111/j.1471-4159.2011.07642.x. PMID 22212065. S2CID 25896721.
- ^ Obovatol and obovatal, novel biphenyl ether lignans from the leaves of Magnolia obovata Thunb. K Ito, T Iida, K Ichino, M Tsunezuka and M Hattori, … and Pharmaceutical Bulletin, 1982